Many people have been asking us if we have the results back from Brandon's DNA testing to determine whether or not his HLA tissue type really does contain two deleted markers. Unfortunately we don't have the answers yet but we are expecting them sometime this week. As soon as we get the results from our hematologist, I'll post them for you.
Basically there will be one of two answers. Either it will be that Brandon does indeed have a normal HLA tissue type and the lab (LabCorps) just didn't identify those two markers the first time around, and if this is the case it means that there should be no reason why he couldn't have a sibling match, we just haven't hit the jackpot yet, or it will show that his body has somehow deleted two of his markers in which case, creating a sibling match would be improbable. These answers will tell us what we are going to do as far as having more children or not.
The way HLA works is that there are four combinations that a set of parents will create. Think of it as type A, B, C and D. Say then that Brandon has type "D". Each full sibling he has thus has a 25% chance of matching him by also being a type "D". So far though Brandon is our only type "D" IF his HLA typing is normal then its just a chance happening we haven't had another "D". And if we kept trying each try would carry the same 25% chance of being the type "D" we want.
But if his body has somehow changed its sequence around and delteted part of the "code" that makes him a type "D" then probably no sibling would ever match that because his "code" would then not be one that we created, but one that his body has morphed into. Does that make any better sense? It's crazy I know... anyhow...still waiting for the answers. Praying for a normal HLA result...
Stalked by the Stork...a diary of raising twelve kids
Sunday, December 21, 2008
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8 comments:
Ugh..... Why can't things ever be easy for you? I am praying for a normal HLA type and that the next child you have will be the one that matches!
Praying that it comes back normal!
I agree with Shar... only you Ang! Only You! UGH!
I don't know Debi and Sharlene...crazy things happen to you guys too! LOL!
love,
ang
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